Singh, U. S. and Kapoor, K. “Introduction to Microbiology,” and “Microbial Cell Structure,” in Introductory Microbiology, 2010. Global Media, Jaipur IND. 2010. eISBN: 9789350431238
Mishra and Agrawal. “Chapter 1: Introduction,” in A Concise Manual of Pathogentic Microbiology, Wiley, Somerset NJ. 2013. eISBN: 9781118301210
Welcome to MIC 100 – Microbiology! This is a fascinating course designed to give students an overview of the microbial world, the beneficial aspects of microbes, and the role of microbes in human disease. We will emphasize the public health aspects of infectious disease, mode of transmission of disease, pathogenicity, inducible host resistance, antigens and antibodies, disease prevention, and the principles of microbial control.
Did you know that during the past century alone more than 500 million people have died of infectious diseases and nearly 5 billion have suffered from debilitating infectious diseases? Compare this number to the less than 100 million people who have died as a result of war-related casualties in the past 500 years. (Mishra and Agrawal 2013).
Microbiology is one of the fundamental areas of knowledge for the health professions. We must know how to identify microorganisms in our environment and how to prevent and control the numerous pathogens that infect virtually everyone on our planet at one time or another. Once we understand the etiology of an infectious disease we are able to not only cure infected persons from the various pathogens found in our environment, but prevent others from becoming infected.
We will begin this course with a review of the history of microbiology and an introduction to cell theory. You will learn how the work of scientists Robert Hooke, Robert Koch, Louis Pasteur, and several others, led to the controversy over spontaneous generation and the understanding of the role of microorganisms in the causation of disease. The work of these pioneers in the field ultimately contributed to the development of cell theory and medical microbiology.
Once you understand the history of microbiology and cell theory, we will learn to identify different kinds of microorganisms and classify them based on certain characteristics. We will consider the concepts of how we classify “species” and how species evolve, as we learn about the classification of microbes into groups such as bacteria, fungi, protozoa, and viruses.
We will then build on this general understanding of microbial biology to examine how our bodies defend against infection and disease, and explore modern concepts of disease control and prevention. In this section we will focus on some current issues surrounding antibiotic resistance (MRSA, VRSA) and STD epidemics facing the human population, such as HIV and HPV, and current attempts to control them. In order to understand why these microbes pose such a risk to our population, we will learn the basics of the human immune response, immunity, and how vaccinations and antibiotics play a role in disease control and prevention.
As we investigate these basic theories of microbiology, we will consider how the human microbiome plays a role in health and disease, and consider the microbiome found in our soil and water. We will address questions such as:
• What are the resident microbiota? What is the difference between a nonpathogenic compared to a pathogenic microbe? What conditions can cause a nonpathogenic microbe to become pathogenic?
• What is metabolism and how do microbes differ in their ability to convert energy into usable forms?
• How does microbial metabolism contribute to biogeochemical cycles?
You will begin each module by completely reading the Home page. The Case Assignment will build on the material contained in the Home page and you will accomplish readings and quizzes in the Boundless Textbook for Microbiology for your SLP assignments. Many additional resources are available to you on your ebrary bookshelf for Microbiology. You may use these to help you accomplish any research for your Case Assignments. Please use the CDC and WHO websites as well as university sites, as these are considered academic sources.
Remember, as you complete your assignments, it is important to clearly document all work submitted in the course. Work should include a title page documenting student’s name, type of assignment (Case or SLP), instructor’s name and the date. All research should be synthesized and presented as ORIGINAL WORK (use your own words!). Adhering to these practices will insure that proper credit is given for each submission. Once again, welcome to Microbiology.
INTRODUCTION TO MICROBIOLOGY
For your first Case Assignment, IN YOUR OWN WORDS, answer these questions reviewing the content in your Course Overview within the Syllabus:
1. What will MIC 100 emphasize?
2. Why is microbiology important to health professionals?
3. How does death by infection compare to death by warfare?
4. What issues surrounding antibiotic resistance are named?
5. What STD epidemics are named?
6. What websites contain excellent resources for this class?
Now answer these questions regarding the material contained on the Module 1 Home Page:
1. Complete this sentence: Infections have killed more humans than…
2. What is the difference between Microbiology and Clinical Microbiology?
3. Name the three defense mechanisms listed.
4. What is a pathogen?
5. What Host-Microbe relations are described?
6. Where do you find the assignments for all of your SLPs?
Cells are the smallest unit of life. All cells are bound by a cell membrane which separates the internal parts of the cell from the external environment.
For the final part of this Case assignment, describe cell theory (hint: there are three components). Briefly describe the work of two scientists that contributed to this theory. Be sure to include your references for this answer.
Watch this video about your cells and answer these questions:
What does the video say is the function of:
Note: The assignment will require you to engage in independent research of cell theory. You will find information on scientists who contributed to this theory in your required reading for your SLP. You will also find additional resources on your ebrary bookshelf, such as the book, Cell Biology: Fundamentals and Applications, a great place to begin your investigation of cell theory and cell biology.
Your assignment is due by the Monday following the end of this module. Please upload your Case Assignment.
Please include a cover sheet for your Case Assignment. Use headings to separate each section’s questions, and answer each question using complete sentences.
References: List the references you used to describe cell theory. Cite them within your text (Author, date) and provide the full reference information in a References section.
Grammar and Spelling: While no points are deducted, assignments are expected to adhere to standard guidelines of grammar, spelling, punctuation, and sentence syntax. Points may be deducted if grammar and spelling impact clarity.
The following items will be assessed:
Assignment-Driven Criteria – Did you address each requirement?
Critical Thinking – How well did you synthesize and evaluate the topics addressed?
Scholarly Writing – Is everything explained in complete sentences?
Quality of References and Assignment Organization – Did you organize your paper with headings?
Citing Sources – Did you list your references and cite information where necessary?